The combined effects of Aloe vera gel and silver nanoparticles on wound healing in rats

Authors

  • A. Shakeri Khalilabad Health Center, Mashhad University of Medical Sciences, Mashhad, Iran
  • B. Bolouri Department of Nanotechnology, College of Advanced Sciences and Technology in Medicine, Tehran University of Medical Sciences, Tehran, Iran|Nanomedine Group, College of Applied Advanced Technology in Medicine, Iran University of Medical Sciences, Tehran, Iran
  • M. Bayati Department of Nanotechnology, College of Advanced Sciences and Technology in Medicine, Tehran University of Medical Sciences, Tehran, Iran
  • Y. Eskandari Khalilabad Health Center, Mashhad University of Medical Sciences, Mashhad, Iran
  • Y. Yousefpoor Department of Nanotechnology, College of Advanced Sciences and Technology in Medicine, Tehran University of Medical Sciences, Tehran, Iran|Nanomedine Group, College of Applied Advanced Technology in Medicine, Iran University of Medical Sciences, Tehran, Iran|Khalilabad Health Center, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract:

Objective(s): This study was aimed at investigating the synergy effects of Aloe vera gel and silver nanoparticles on the healing rate of the cutting wounds. Materials and Methods: In order to determine the concentration of silver nanoparticles in Aloe vera gel, the MBC methods were applied on the most common bacteria infecting wounds, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa. The cutting wounds with Full-thickness skin were dorsally created on rats; then the rats were divided into 4 groups. The treatments groups included: mixture of Aloe vera gel and silver nanoparticles, Aloe vera gel alone and silver nanoparticles alone in addition to control groups. The treatment was carried out for 2 weeks and the size of the wound closures were measured by an image software analysis. Results:There was no significant difference (p

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Journal title

volume 3  issue 1

pages  57- 64

publication date 2016-01-01

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